Nice View of CleanEx Exp : GSE360_DOC

[General] [References] [Expression data]

General information about the entry

Dataset code	GSE360
Dataset Title	Macrophages and dendritic cells exposed to phylogenetically distinct parasites
Description	Monocyte-derived dendritic cells (DC) and macrophages (MΦ) generated in vitro from the same individual blood donors were exposed to five different pathogens, and gene expression profiles were assessed by microarray analysis. Responses to Mycobacterium tuberculosis and to phylogenetically distinct protozoan (Leishmania major, L. donovani, Toxoplasma gondii) and helminth (Brugia malayi) parasites were examined, each of which produces chronic infections in humans yet vary considerably in the nature of the immune responses they trigger..
Organism	Homo sapiens
Format Type	Intensity Affymetrix;HG-U95A
Number of Experiments	28
Maximum log	10.7516392090833
Minimum log	-4.89662312566542

References

Original URL	http://www.ncbi.nlm.nih.gov/projects/geo/query/acc.cgi?acc=GSE360
Paper Reference	Chaussabel D et al. Blood. 2003 Jul 15;102(2):672-81. Epub 2003 Mar 27.
MEDLINE Reference	12663451

Experiments

Experiment number	Experiment Code	Experiment Description
1	GSE360_GSM5123	Dendritic Cells, Baseline - Repeat #1;src:Monocyte-derived Dendritic Cells, Untreated;cell type=dendritic;infection=control;";
2	GSE360_GSM5125	Dendritic Cells, Exposed to Leishmania donovani - Repeat #1;src:Monocyte-derived Dendritic Cells, Exposed to the intracellular protozan parasite Leishmania donovani for 18 hours;cell type=dendritic;infection=Leishmania donovani;";
3	GSE360_GSM5128	Dendritic Cells, Exposed to Leishmania major - Repeat #1;src:Monocyte-derived Dendritic Cells, Exposed to the intracellular protozan parasite Leishmania major for 18 hours;cell type=dendritic;infection=Leishmania major;";
4	GSE360_GSM5129	Dendritic Cells, Exposed to Toxoplasma gondii - Repeat #1;src:Monocyte-derived Dendritic Cells, Exposed to the intracellular protozan parasite Toxoplasma gondii for 18 hours;cell type=dendritic;infection=Toxoplasma gondii;";
5	GSE360_GSM5132	Dendritic Cells, Exposed to Brugia malayi (50) - Repeat #1;src:Monocyte-derived Dendritic Cells, Exposed to the extracellular worm parasite Brugia malyi (50 worms/well) for 18 hours;cell type=dendritic;infection=Brugia malyi (50);";
6	GSE360_GSM5134	Dendritic Cells, Exposed to Brugia malayi (5) - Repeat #1;src:Monocyte-derived Dendritic Cells, Exposed to the extracellular worm parasite Brugia malyi (5 worms/well) for 18 hours;cell type=dendritic;infection=Brugia malyi (5);";
7	GSE360_GSM5135	Dendritic Cells, Exposed to Mycobacterium tuberculosis - Repeat #1;src:Monocyte-derived Dendritic Cells, Exposed to the Mycobacterium tuberculosis bacilli for 18 hours;cell type=dendritic;infection=Mycobacterium tuberculosis;";
8	GSE360_GSM5136	Dendritic Cells, Baseline - Repeat #2;src:Monocyte-derived Dendritic Cells, Untreated;cell type=dendritic;infection=control;";
9	GSE360_GSM5137	Dendritic Cells, Exposed to Leishmania major - Repeat #2;src:Monocyte-derived Dendritic Cells, Exposed to the intracellular protozan parasite Leishmania major for 18 hours;cell type=dendritic;infection=Leishmania major;";
10	GSE360_GSM5138	Dendritic Cells, Exposed to Leishmania donovani - Repeat #2;src:Monocyte-derived Dendritic Cells, Exposed to the intracellular protozan parasite Leishmania donovani for 18 hours;cell type=dendritic;infection=Leishmania donovani;";
11	GSE360_GSM5139	Dendritic Cells, Exposed to Toxoplasma gondii - Repeat #2;src:Monocyte-derived Dendritic Cells, Exposed to the intracellular protozan parasite Toxoplasma gondii for 18 hours;cell type=dendritic;infection=Toxoplasma gondii;";
12	GSE360_GSM5140	Dendritic Cells, Exposed to Brugia malayi (50) - Repeat #2;src:Monocyte-derived Dendritic Cells, Exposed to the extracellular worm parasite Brugia malyi (50 worms/well) for 18 hours;cell type=dendritic;infection=Brugia malyi (50);";
13	GSE360_GSM5141	Dendritic Cells, Exposed to Brugia malayi (5) - Repeat #2;src:Monocyte-derived Dendritic Cells, Exposed to the extracellular worm parasite Brugia malyi (5 worms/well) for 18 hours;cell type=dendritic;infection=Brugia malyi (5);";
14	GSE360_GSM5142	Dendritic Cells, Exposed to Mycobacterium tuberculosis - Repeat #2;src:Monocyte-derived Dendritic Cells, Exposed to the Mycobacterium tuberculosis bacilli for 18 hours;cell type=dendritic;infection=Mycobacterium tuberculosis;";
15	GSE360_GSM5143	Macrophages, Baseline - Repeat #1;src:Monocyte-derived Macrophages, Untreated;cell type=macrophage;infection=control;";
16	GSE360_GSM5144	Macrophages, Exposed to Leishmania major - Repeat #1;src:Monocyte-derived Macrophages, Exposed to the intracellular protozan parasite Leishmania major for 18 hours;cell type=macrophage;infection=Leishmania major;";
17	GSE360_GSM5145	Macrophages, Exposed to Leishmania donovani - Repeat #1;src:Monocyte-derived Macrophages, Exposed to the intracellular protozan parasite Leishmania donovani for 18 hours;cell type=macrophage;infection=Leishmania donovani;";
18	GSE360_GSM5146	Macrophages, Exposed to Toxoplasma gondii - Repeat #1;src:Monocyte-derived Macrophages, Exposed to the intracellular protozan parasite Toxoplasma gondii for 18 hours;cell type=macrophage;infection=Toxoplasma gondii;";
19	GSE360_GSM5147	Macrophages, Exposed to Brugia malayi (50) - Repeat #1;src:Monocyte-derived Macrophages, Exposed to the extracellular worm parasite Brugia malyi (50 worms/well) for 18 hours;cell type=macrophage;infection=Brugia malyi (50);";
20	GSE360_GSM5148	Macrophages, Exposed to Brugia malayi (5) - Repeat #1;src:Monocyte-derived Macrophages, Exposed to the extracellular worm parasite Brugia malyi (5 worms/well) for 18 hours;cell type=macrophage;infection=Brugia malyi (5);";
21	GSE360_GSM5149	Macrophages, Exposed to Mycobacterium tuberculosis - Repeat #1;src:Monocyte-derived Macrophages, Exposed to the Mycobacterium tuberculosis bacilli for 18 hours;cell type=macrophage;infection=Mycobacterium tuberculosis;";
22	GSE360_GSM5150	Macrophages, Baseline - Repeat #2;src:Monocyte-derived Macrophages, Untreated;cell type=macrophage;infection=control;";
23	GSE360_GSM5151	Macrophages, Exposed to Leishmania major - Repeat #2;src:Monocyte-derived Macrophages, Exposed to the intracellular protozan parasite Leishmania major for 18 hours;cell type=macrophage;infection=Leishmania major;";
24	GSE360_GSM5152	Macrophages, Exposed to Leishmania donovani - Repeat #2;src:Monocyte-derived Macrophages, Exposed to the intracellular protozan parasite Leishmania donovani for 18 hours;cell type=macrophage;infection=Leishmania donovani;";
25	GSE360_GSM5153	Macrophages, Exposed to Toxoplasma gondii - Repeat #2;src:Monocyte-derived Macrophages, Exposed to the intracellular protozan parasite Toxoplasma gondii for 18 hours;cell type=macrophage;infection=Toxoplasma gondii;";
26	GSE360_GSM5154	Macrophages, Exposed to Brugia malayi (50) - Repeat #2;src:Monocyte-derived Macrophages, Exposed to the extracellular worm parasite Brugia malyi (50 worms/well) for 18 hours;cell type=macrophage;infection=Brugia malyi (50);";
27	GSE360_GSM5155	Macrophages, Exposed to Brugia malayi (5) - Repeat #2;src:Monocyte-derived Macrophages, Exposed to the extracellular worm parasite Brugia malyi (5 worms/well) for 18 hours;cell type=macrophage;infection=Brugia malyi (5);";
28	GSE360_GSM5156	Macrophages, Exposed to Mycobacterium tuberculosis - Repeat #2;src:Monocyte-derived Macrophages, Exposed to the Mycobacterium tuberculosis bacilli for 18 hours;cell type=macrophage;infection=Mycobacterium tuberculosis;";