Nice View of CleanEx Exp : GSE2251_DOC

[General] [References] [Expression data]

General information about the entry
Dataset code GSE2251
Dataset Title Anti-prolif. effect of E2 in breast cancer cells that re-exp. ERalpha is mediated by aberr. regulat. of cell cycle genes
Description Gene expression changes caused by estrogen treatment of breast cancer cells that re-express ERalpha was investigated by infecting ER-negative MDA-MB-231 breast cancer cells for 24 h with recombinant adenovirus encoding full-length human ERalpha (Ad-ERalpha) or control vector (Ad-LacZ), and treating them with 0ยท01% ethanol (vehicle control) or 10-8 M 17beta-estradiol (E2). After 48 h of treatment, total RNA was isolated and used for transcript profiling on Affymetrix GeneChips. Three independent biological replicates of this experiment were carried out..
Organism Homo sapiens
Format Type Intensity
Affymetrix;HG-U133A
Number of Experiments 12
Maximum log 7.84195756608991
Minimum log -7.65491992316521
References
Original URL http://www.ncbi.nlm.nih.gov/projects/geo/query/acc.cgi?acc=GSE2251
Paper Reference Moggs JG et al. J Mol Endocrinol. 2005 Apr;34(2):535-51.
MEDLINE Reference 15821115
Experiments
Experiment numberExperiment CodeExperiment Description
1GSE2251_GSM41346AdERalpha+E2-8 JM3;src:MDA-MB-231;protocol=ERalpha expression;agent=E2;";
2GSE2251_GSM41347AdERalpha+E2-8 JMTM5;src:MDA-MB-231;protocol=ERalpha expression;agent=E2;";
3GSE2251_GSM41348AdERalpha+E2-8 JMTM19;src:MDA-MB-231;protocol=ERalpha expression;agent=E2;";
4GSE2251_GSM41349AdERalpha+vehicle JM1;src:MDA-MB-231;protocol=ERalpha expression;agent=control;";
5GSE2251_GSM41350AdERalpha+vehicle JMTM4;src:MDA-MB-231;protocol=ERalpha expression;agent=control;";
6GSE2251_GSM41351AdERalpha+vehicle JMTM18;src:MDA-MB-231;protocol=ERalpha expression;agent=control;";
7GSE2251_GSM41352AdLacZ+E2-8 JM6;src:MDA-MB-231;protocol=control;agent=E2;";
8GSE2251_GSM41353AdLacZ+E2-8 JMTM2;src:MDA-MB-231;protocol=control;agent=E2;";
9GSE2251_GSM41354AdLacZ+E2-8 JMTM17;src:MDA-MB-231;protocol=control;agent=E2;";
10GSE2251_GSM41355AdLacZ+vehicle JM4;src:MDA-MB-231;protocol=control;agent=control;";
11GSE2251_GSM41356AdLacZ+vehicle JMTM1;src:MDA-MB-231;protocol=control;agent=control;";
12GSE2251_GSM41357AdLacZ+vehicle JMTM16;src:MDA-MB-231;protocol=control;agent=control;";