Nice View of CleanEx Exp : GSE1363_DOC

[General] [References] [Expression data]

General information about the entry

Dataset code	GSE1363
Dataset Title	Gene expression in T1alpha null mutant lungs compared to wild type at dpc 18.5 and term
Description	We compared gene expression in T1alpha (-/-) lungs vs wild type at dpc 18.5 when the phenotype is moderate and at term when the phenotype is more severe. Lungs present narrow and irregular alveolar spaces, thicker mesenchyme, reduced number of attenuated type I cells, normal numbers of type II cells and secreted surfactant. At term, but not a dpc 18.5, there is increased proliferation of distal cells. We compared gene expression of T1alpha null mutant lungs to wild type lungs at dpc 18.5. The mutant phenotype at this developmental stage is moderate but the alveolar sacs are narrower than normal..
Organism	Mus musculus
Format Type	Intensity Affymetrix;MG-U74Av2
Number of Experiments	16
Maximum log	9.70026184476835
Minimum log	-6.00278259944909

References

Original URL	http://www.ncbi.nlm.nih.gov/projects/geo/query/acc.cgi?acc=GSE1363
MEDLINE Reference	Not available

Experiments

Experiment number	Experiment Code	Experiment Description
1	GSE1363_GSM22035	sample A 18.5 homo;src:T1alpha (-/-) fetal lung dpc 18.5;development stage=18.5 dpc;genotype/variation=T1alpha null;";
2	GSE1363_GSM22036	sample B 18.5 homo;src:T1alpha (-/-) fetal lung dpc 18.5;development stage=18.5 dpc;genotype/variation=T1alpha null;";
3	GSE1363_GSM22037	sample C 18.5 homo;src:T1alpha (-/-) fetal lung dpc 18.5;development stage=18.5 dpc;genotype/variation=T1alpha null;";
4	GSE1363_GSM22038	sample D 18.5 homo;src:T1alpha (-/-) fetal lung dpc 18.5;development stage=18.5 dpc;genotype/variation=T1alpha null;";
5	GSE1363_GSM22039	sample E 18.5 homo;src:T1alpha (-/-) fetal lung dpc 18.5;development stage=18.5 dpc;genotype/variation=T1alpha null;";
6	GSE1363_GSM22040	sample F term homo;src:T1alpha (-/-) lung at birth (term);development stage=birth;genotype/variation=T1alpha null;";
7	GSE1363_GSM22041	sample G term homo;src:T1alpha (-/-) lung at birth (term);development stage=birth;genotype/variation=T1alpha null;";
8	GSE1363_GSM22042	sample H term homo;src:T1alpha (-/-) lung at birth (term);development stage=birth;genotype/variation=T1alpha null;";
9	GSE1363_GSM22043	sample I 18.5 wt;src:Wild type fetal lung dpc 18.5;development stage=18.5 dpc;genotype/variation=wild type;";
10	GSE1363_GSM22044	sample J 18.5 wt;src:Wild type fetal lung dpc 18.5;development stage=18.5 dpc;genotype/variation=wild type;";
11	GSE1363_GSM22045	sample K 18.5 wt;src:Wild type fetal lung dpc 18.5;development stage=18.5 dpc;genotype/variation=wild type;";
12	GSE1363_GSM22046	sample L 18.5 wt;src:Wild type fetal lung dpc 18.5;development stage=18.5 dpc;genotype/variation=wild type;";
13	GSE1363_GSM22047	sample M 18.5 wt;src:Wild type fetal lung dpc 18.5;development stage=18.5 dpc;genotype/variation=wild type;";
14	GSE1363_GSM22048	sample N term wt;src:Wild type lung at birth (term);development stage=birth;genotype/variation=wild type;";
15	GSE1363_GSM22049	sample O term wt;src:Wild type lung at birth (term);development stage=birth;genotype/variation=wild type;";
16	GSE1363_GSM22050	sample P term wt;src:Wild type lung at birth (term);development stage=birth;genotype/variation=wild type;";