Nice View of CleanEx Exp : GSE10072_DOC

[General] [References] [Expression data]

General information about the entry
Dataset code GSE10072
Dataset Title Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival
Description Tobacco smoking is responsible for over 90% of lung cancer cases, and yet the precise molecular alterations induced by smoking in lung that develop into cancer and impact survival have remained obscure. We performed gene expression analysis using HG-U133A Affymetrix chips on 135 fresh frozen tissue samples of adenocarcinoma and paired noninvolved lung tissue from current, former and never smokers, with biochemically validated smoking information. ANOVA analysis adjusted for potential confounders, multiple testing procedure, Gene Set Enrichment Analysis, and GO-functional classification were conducted for gene selection. Results were confirmed in independent adenocarcinoma and non-tumor tissues from two studies. We identified a gene expression signature characteristic of smoking that includes cell cycle genes, particularly those involved in the mitotic spindle formation (e.g., NEK2, TTK, PRC1). Expression of these genes strongly differentiated both smokers from non-smokers in lung tumors and early stage tumor tissue from non-tumor tissue (p<0.001 and fold-change>1.5, for each comparison), consistent with an important role for this pathway in lung carcinogenesis induced by smoking. These changes persisted many years after smoking cessation. NEK2 (p<0.001) and TTK (p=0.002) expression in the noninvolved lung tissue was also associated with a 3-fold increased risk of mortality from lung adenocarcinoma in smokers. Our work provides insight into the smoking-related mechanisms of lung neoplasia, and shows that the very mitotic genes known to be involved in cancer development are induced by smoking and affect survival. These genes are candidate targets for chemoprevention and treatment of lung cancer in smokers..
Organism Homo sapiens
Format Type Intensity
Affymetrix;HG-U133A
Number of Experiments 107
Maximum log 7.72109119543736
Minimum log -3.8570753821291
References
Original URL http://www.ncbi.nlm.nih.gov/projects/geo/query/acc.cgi?acc=GSE10072
MEDLINE Reference Not available
Experiments
Experiment numberExperiment CodeExperiment Description
1GSE10072_GSM254625Lung Tumor_GT00006;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 69;Cigarette Smoking Status: Never Smoked;Stage:IIB";
2GSE10072_GSM254626Normal Lung_GT00006;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 69;Cigarette Smoking Status: Never Smoked;Stage:IIB";
3GSE10072_GSM254627Lung Tumor_GT00007;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 68;Cigarette Smoking Status: Former Smoker;Stage:IIB";
4GSE10072_GSM254628Normal Lung_GT00007;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 68;Cigarette Smoking Status: Former Smoker;Stage:IIB";
5GSE10072_GSM254629Lung Tumor_GT00022;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 74;Cigarette Smoking Status: Never Smoked;Stage:IB";
6GSE10072_GSM254630Lung Tumor_GT00042;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 75;Cigarette Smoking Status: Former Smoker;Stage:IIA";
7GSE10072_GSM254631Lung Tumor_GT00059;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 67;Cigarette Smoking Status: Former Smoker;Stage:IIIA";
8GSE10072_GSM254632Normal Lung_GT00059;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 67;Cigarette Smoking Status: Former Smoker;Stage:IIIA";
9GSE10072_GSM254633Lung Tumor_GT00146;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 71;Cigarette Smoking Status: Former Smoker;Stage:IIB";
10GSE10072_GSM254634Normal Lung_GT00146;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 71;Cigarette Smoking Status: Former Smoker;Stage:IIB";
11GSE10072_GSM254635Normal Lung_GT01001;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 70;Cigarette Smoking Status: Never Smoked;Stage:IIIB";
12GSE10072_GSM254636Lung Tumor_GT01001;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 70;Cigarette Smoking Status: Never Smoked;Stage:IIIB";
13GSE10072_GSM254637Lung Tumor_GT01003;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 45;Cigarette Smoking Status: Current Smoker;Stage:IV";
14GSE10072_GSM254638Normal Lung_GT01003;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 45;Cigarette Smoking Status: Current Smoker;Stage:IV";
15GSE10072_GSM254639Lung Tumor_GT01011;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 67;Cigarette Smoking Status: Never Smoked;Stage:IIB";
16GSE10072_GSM254640Normal Lung_GT01011;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 67;Cigarette Smoking Status: Never Smoked;Stage:IIB";
17GSE10072_GSM254641Lung Tumor_GT01017;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 65;Cigarette Smoking Status: Current Smoker;Stage:IIB";
18GSE10072_GSM254642Lung Tumor_GT01019;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 66;Cigarette Smoking Status: Current Smoker;Stage:IIB";
19GSE10072_GSM254643Normal Lung_GT01024;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 61;Cigarette Smoking Status: Never Smoked;Stage:IA";
20GSE10072_GSM254644Normal Lung_GT01025;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 65;Cigarette Smoking Status: Current Smoker;Stage:IA";
21GSE10072_GSM254645Lung Tumor_GT01025;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 65;Cigarette Smoking Status: Current Smoker;Stage:IA";
22GSE10072_GSM254646Normal Lung_GT01033;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 73;Cigarette Smoking Status: Former Smoker;Stage:IIB";
23GSE10072_GSM254647Lung Tumor_GT01034;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 73;Cigarette Smoking Status: Current Smoker;Stage:IIB";
24GSE10072_GSM254648Lung Tumor_GT01036;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 67;Cigarette Smoking Status: Never Smoked;Stage:IB";
25GSE10072_GSM254649Normal Lung_GT01036;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 67;Cigarette Smoking Status: Never Smoked;Stage:IB";
26GSE10072_GSM254650Lung Tumor_GT01038;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 46;Cigarette Smoking Status: Current Smoker;Stage:IIIA";
27GSE10072_GSM254651Normal Lung_GT01038;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 46;Cigarette Smoking Status: Current Smoker;Stage:IIIA";
28GSE10072_GSM254652Lung Tumor_GT01040;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 71;Cigarette Smoking Status: Never Smoked;Stage:IIB";
29GSE10072_GSM254653Normal Lung_GT01047;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 59;Cigarette Smoking Status: Never Smoked;Stage:IIIA";
30GSE10072_GSM254654Lung Tumor_GT01049;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 79;Cigarette Smoking Status: Former Smoker;Stage:IIIA";
31GSE10072_GSM254655Normal Lung_GT01051;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 66;Cigarette Smoking Status: Former Smoker;Stage:IB";
32GSE10072_GSM254656Lung Tumor_GT01052;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 56;Cigarette Smoking Status: Former Smoker;Stage:IIIA";
33GSE10072_GSM254657Lung Tumor_GT01054;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 71;Cigarette Smoking Status: Former Smoker;Stage:IIIB";
34GSE10072_GSM254658Normal Lung_GT01061;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 68;Cigarette Smoking Status: Never Smoked;Stage:IIIA";
35GSE10072_GSM254659Lung Tumor_GT01061;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 68;Cigarette Smoking Status: Never Smoked;Stage:IIIA";
36GSE10072_GSM254660Normal Lung_GT01064;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 71;Cigarette Smoking Status: Never Smoked;Stage:IB";
37GSE10072_GSM254661Lung Tumor_GT01077;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 59;Cigarette Smoking Status: Current Smoker;Stage:IIA";
38GSE10072_GSM254662Normal Lung_GT01085;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 65;Cigarette Smoking Status: Former Smoker;Stage:IIIA";
39GSE10072_GSM254663Lung Tumor_GT01087;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 58;Cigarette Smoking Status: Current Smoker;Stage:IIB";
40GSE10072_GSM254664Lung Tumor_GT01089;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 62;Cigarette Smoking Status: Former Smoker;Stage:IIIB";
41GSE10072_GSM254665Normal Lung_GT01095;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 61;Cigarette Smoking Status: Current Smoker;Stage:IB";
42GSE10072_GSM254666Lung Tumor_GT01097;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 59;Cigarette Smoking Status: Current Smoker;Stage:IA";
43GSE10072_GSM254667Normal Lung_GT01097;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 59;Cigarette Smoking Status: Current Smoker;Stage:IA";
44GSE10072_GSM254668Lung Tumor_GT01099;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 71;Cigarette Smoking Status: Former Smoker;Stage:IB";
45GSE10072_GSM254669Normal Lung_GT01099;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 71;Cigarette Smoking Status: Former Smoker;Stage:IB";
46GSE10072_GSM254670Lung Tumor_GT01100;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 69;Cigarette Smoking Status: Former Smoker;Stage:IIB";
47GSE10072_GSM254671Normal Lung_GT01100;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 69;Cigarette Smoking Status: Former Smoker;Stage:IIB";
48GSE10072_GSM254672Lung Tumor_GT01103;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 64;Cigarette Smoking Status: Current Smoker;Stage:IB";
49GSE10072_GSM254673Normal Lung_GT01105;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 61;Cigarette Smoking Status: Never Smoked;Stage:IV";
50GSE10072_GSM254674Lung Tumor_GT01105;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 61;Cigarette Smoking Status: Never Smoked;Stage:IV";
51GSE10072_GSM254675Lung Tumor_GT01107;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 59;Cigarette Smoking Status: Current Smoker;Stage:IA";
52GSE10072_GSM254676Normal Lung_GT01107;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 59;Cigarette Smoking Status: Current Smoker;Stage:IA";
53GSE10072_GSM254677Normal Lung_GT01113;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 63;Cigarette Smoking Status: Former Smoker;Stage:IIIB";
54GSE10072_GSM254678Lung Tumor_GT01117;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 63;Cigarette Smoking Status: Current Smoker;Stage:IB";
55GSE10072_GSM254679Normal Lung_GT01117;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 63;Cigarette Smoking Status: Current Smoker;Stage:IB";
56GSE10072_GSM254680Lung Tumor_GT01119;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 74;Cigarette Smoking Status: Never Smoked;Stage:IIIA";
57GSE10072_GSM254681Normal Lung_GT01119;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 74;Cigarette Smoking Status: Never Smoked;Stage:IIIA";
58GSE10072_GSM254682Lung Tumor_GT01120;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 51;Cigarette Smoking Status: Current Smoker;Stage:IIB";
59GSE10072_GSM254683Normal Lung_GT01120;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 51;Cigarette Smoking Status: Current Smoker;Stage:IIB";
60GSE10072_GSM254684Lung Tumor_GT01121;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 52;Cigarette Smoking Status: Current Smoker;Stage:IV";
61GSE10072_GSM254685Normal Lung_GT01121;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 52;Cigarette Smoking Status: Current Smoker;Stage:IV";
62GSE10072_GSM254686Lung Tumor_GT01124;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 68;Cigarette Smoking Status: Never Smoked;Stage:IIIA";
63GSE10072_GSM254687Lung Tumor_GT01126;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 60;Cigarette Smoking Status: Current Smoker;Stage:IIIA";
64GSE10072_GSM254688Lung Tumor_GT01127;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 73;Cigarette Smoking Status: Current Smoker;Stage:IB";
65GSE10072_GSM254689Normal Lung_GT01128;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 66;Cigarette Smoking Status: Current Smoker;Stage:IB";
66GSE10072_GSM254690Lung Tumor_GT01128;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 66;Cigarette Smoking Status: Current Smoker;Stage:IB";
67GSE10072_GSM254691Normal Lung_GT01129;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 55;Cigarette Smoking Status: Current Smoker;Stage:IB";
68GSE10072_GSM254692Lung Tumor_GT01129;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 55;Cigarette Smoking Status: Current Smoker;Stage:IB";
69GSE10072_GSM254693Normal Lung_GT01130;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 71;Cigarette Smoking Status: Never Smoked;Stage:IB";
70GSE10072_GSM254694Lung Tumor_GT01130;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 71;Cigarette Smoking Status: Never Smoked;Stage:IB";
71GSE10072_GSM254695Normal Lung_GT01131;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 64;Cigarette Smoking Status: Never Smoked;Stage:IA";
72GSE10072_GSM254696Lung Tumor_GT01135;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 60;Cigarette Smoking Status: Current Smoker;Stage:IB";
73GSE10072_GSM254697Lung Tumor_GT01148;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 69;Cigarette Smoking Status: Former Smoker;Stage:IB";
74GSE10072_GSM254698Lung Tumor_GT01151;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 80;Cigarette Smoking Status: Current Smoker;Stage:IIA";
75GSE10072_GSM254699Normal Lung_GT01156;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 73;Cigarette Smoking Status: Former Smoker;Stage: IB";
76GSE10072_GSM254700Lung Tumor_GT01175;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 62;Cigarette Smoking Status: Never Smoked;Stage:IIB";
77GSE10072_GSM254701Lung Tumor_GT01182;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 78;Cigarette Smoking Status: Never Smoked;Stage:IB";
78GSE10072_GSM254702Normal Lung_GT01182;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 78;Cigarette Smoking Status: Never Smoked;Stage:IB";
79GSE10072_GSM254703Normal Lung_GT01194;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 67;Cigarette Smoking Status: Former Smoker;Stage:IB";
80GSE10072_GSM254704Lung Tumor_GT01194;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 67;Cigarette Smoking Status: Former Smoker;Stage:IB";
81GSE10072_GSM254705Lung Tumor_GT01222;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 63;Cigarette Smoking Status: Current Smoker;Stage:IB";
82GSE10072_GSM254706Normal Lung_GT01222;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 63;Cigarette Smoking Status: Current Smoker;Stage:IB";
83GSE10072_GSM254707Lung Tumor_GT01232;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 81;Cigarette Smoking Status: Former Smoker;Stage:IB";
84GSE10072_GSM254708Normal Lung_GT01232;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 81;Cigarette Smoking Status: Former Smoker;Stage:IB";
85GSE10072_GSM254709Lung Tumor_GT01233;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 57;Cigarette Smoking Status: Current Smoker;Stage:IIB";
86GSE10072_GSM254710Normal Lung_GT01233;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 57;Cigarette Smoking Status: Current Smoker;Stage:IIB";
87GSE10072_GSM254711Normal Lung_GT01237;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 60;Cigarette Smoking Status: Former Smoker;Stage:IIB";
88GSE10072_GSM254712Normal Lung_GT01239;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 65;Cigarette Smoking Status: Current Smoker;Stage:IA";
89GSE10072_GSM254713Normal Lung_GT01240;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 75;Cigarette Smoking Status: Current Smoker;Stage:IB";
90GSE10072_GSM254714Lung Tumor_GT01243;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 73;Cigarette Smoking Status: Former Smoker;Stage:IA";
91GSE10072_GSM254715Normal Lung_GT01243;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 73;Cigarette Smoking Status: Former Smoker;Stage:IA";
92GSE10072_GSM254716Lung Tumor_GT01246;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 76;Cigarette Smoking Status: Former Smoker;Stage:IIB";
93GSE10072_GSM254717Normal Lung_GT01246;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 76;Cigarette Smoking Status: Former Smoker;Stage:IIB";
94GSE10072_GSM254718Lung Tumor_GT01247;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 62;Cigarette Smoking Status: Never Smoked;Stage:IIIA";
95GSE10072_GSM254719Normal Lung_GT01247;Gene expression data;Normal Lung Tissue;Gender: Female;Age at Diagnosis: 62;Cigarette Smoking Status: Never Smoked;Stage:IIIA";
96GSE10072_GSM254720Lung Tumor_GT01274;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 75;Cigarette Smoking Status: Former Smoker;Stage:IIB";
97GSE10072_GSM254721Lung Tumor_GT01276;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 73;Cigarette Smoking Status: Current Smoker;Stage:IIB";
98GSE10072_GSM254722Lung Tumor_GT01279;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 74;Cigarette Smoking Status: Former Smoker;Stage:IB";
99GSE10072_GSM254723Normal Lung_GT01283;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 77;Cigarette Smoking Status: Former Smoker;Stage:IIB";
100GSE10072_GSM254724Lung Tumor_GT01411;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 63;Cigarette Smoking Status: Current Smoker;Stage:IIB";
101GSE10072_GSM254725Normal Lung_GT01417;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 69;Cigarette Smoking Status: Current Smoker;Stage:IIA";
102GSE10072_GSM254726Lung Tumor_GT01421;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 68;Cigarette Smoking Status: Never Smoked;Stage:IB";
103GSE10072_GSM254727Normal Lung_GT01421;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 68;Cigarette Smoking Status: Never Smoked;Stage:IB";
104GSE10072_GSM254728Lung Tumor_GT01425;Gene expression data;Adenocarcinoma of the Lung;Gender: Female;Age at Diagnosis: 72;Cigarette Smoking Status: Never Smoked;Stage:IA";
105GSE10072_GSM254729Lung Tumor_GT01445;Gene expression data;Adenocarcinoma of the Lung;Gender: Male;Age at Diagnosis: 70;Cigarette Smoking Status: Former Smoker;Stage:IIB";
106GSE10072_GSM254730Normal Lung_GT01445;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 70;Cigarette Smoking Status: Former Smoker;Stage:IIB";
107GSE10072_GSM254731Normal Lung_GT01479;Gene expression data;Normal Lung Tissue;Gender: Male;Age at Diagnosis: 63;Cigarette Smoking Status: Former Smoker;Stage:IIB";